38 Comments
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Roger Beal's avatar

In the opinion of this active 77 y/o male, the biggest risk to good elder health is the one you named above: IMMOBILITY.

Sit on your duff all day and almost everything deteriorates faster, from joints to BMI to mental acuity. It's not hard to spot those in my generation who bought into the lie about retiring early and taking it easy. Many of them are lardlocked, and complain mightily about aches and pains.

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Dani Richards's avatar

and very sadly, I see it among even younger people -- as soon as they turn 50, it seems. My friends I've known my entire life are now quite "old," and I feel, for the most part, as young as I did in my 30s. They are all retiring early, and I plan to never retire. I might downsize my work to part-time, to enjoy grandkids, but otherwise.... I can't imagine the atrophy of just sitting around. I choose as role models people in their 90s who are living independently, active minds, good eyesight and hearing. What do they have in common? They don't take prescriptions, they eat nourishing foods, and they walk a lot and move in other ways (chores, tai chi, weight lifting, etc.). They also don't live in retirement communities......

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Coalburned's avatar

100% agree. I've personally seen it happen too many times for it to be coincidence.

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Roman S Shapoval's avatar

Let's not forget statins, which can also lead to muscle wasting and calcium disruption, combined with EMF, which pulls calcium from bone (space osteoporosis)

https://romanshapoval.substack.com/i/139666175/are-you-the-carpenter-of-your-copper-dna-destiny

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Vonu's avatar

The MK-7 version of vitamin K2 returns calcium to the bones from blood, where it causes arteriosclerosis.

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Nod's avatar

except when you drink fluoride every day

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Vonu's avatar

Any systemic poison would be equally deleterious.

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KarlM Alias's avatar

Should be trans, not cis.

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Rosalind McGill's avatar

My ( not insurance dictated)integrative medicine doctor gives me a bio identical hormone. I’m 59 & the doctors in the system want me on the osteoporosis rx . Never!

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Vonu's avatar

The integrative RX for osteoporosis is the MK-7 version of vitamin K2.

There is a reason why MK-7 is paired with D3.

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Rosalind McGill's avatar

I take d& k. Integrative medicine Dr.now. My insurance dictated doctors, it was like pulling teeth to get my psychiatrist to measure my d levels and I was living in upstate New York and had seasonal depression.. crazy system not designed for our health, just profit and chronic illness” management”.

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Vonu's avatar

Why would a psychiatrist need to know the blood level of anything but psychiatric drugs? There are now services where all you have to do is have blood drawn and pay a fee to have a lab produce whatever kind of report you what sent to you by email.

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moons13's avatar
2dEdited

My husband and myself are Neuromuscular massage therapist. In our training we learned about nutrient foramen. This is where nutrients enter the bones. There is one in the upper third of the femur and there is one in the mandible. We believe that the bisphosphonates cause dead bone

tissue to block these nutrient foramen so the bone will necrosis in these areas leading to fractures.

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Fred's avatar
2dEdited

Osteoporosis is real; previously physically fit relative just died with a spine folded over on itself. Strontium ranelate showed great promise, until the "new" drugs came on the market, and suddenly it caused heart attacks in the elderly, sedentary women. (Did they find they couldn't patent it? IDK). Note that the strontium available in the USA is strontium citrate, and it is not effective.

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Fred's avatar
2dEdited

Evidence from both sides of the argument:

Strontium ranelate, a strontium(II) salt of ranelic acid. If I had to guess, the change from “safe and effective” to, “you can’t have it,” may have something to do with inability to patent natural ingredients? IDK. The terribly expensive drugs available in the USA are terrible imho.

https://pubmed.ncbi.nlm.nih.gov/29924137/ (helpful in OA)

https://strwebprdmedia.blob.core.windows.net/media/prvhadyx/ros-strontium-ranelate.pdf

https://www.sciencedirect.com/science/article/pii/S0928493116319488?ref=pdf_download&fr=RR-2&rr=939daa6b1bca2f03

https://pubmed.ncbi.nlm.nih.gov/12171530/

https://pubmed.ncbi.nlm.nih.gov/16787205/

“All these results suggest that strontium ranelate is a new, effective and safe treatment of vertebral and non-vertebral osteoporosis, with a unique mode of action.”

https://pubmed.ncbi.nlm.nih.gov/15578158/

“Strontium ranelate thus offers significant clinical benefits in terms of efficacy, tolerability, and ease of administration in the treatment of postmenopausal women with vertebral osteoporotic fractures.”

https://pubmed.ncbi.nlm.nih.gov/15728210/

“Strontium ranelate increased bone mineral density throughout the study, reaching at 3 yr (P < 0.001): +8.2% (femoral neck) and +9.8% (total hip). Incidence of adverse events (AEs) was similar in both groups.

Conclusion: This study shows that strontium ranelate significantly reduces the risk of all nonvertebral and in a high-risk subgroup, hip fractures over a 3-yr period, and is well tolerated. It confirms that strontium ranelate reduces vertebral fractures. Strontium ranelate offers a safe and effective means of reducing the risk of fracture associated with osteoporosis.

https://pubmed.ncbi.nlm.nih.gov/14749454/

“Strontium ranelate increased bone mineral density at month 36 by 14.4 percent at the lumbar spine and 8.3 percent at the femoral neck (P<0.001 for both comparisons). There were no significant differences between the groups in the incidence of serious adverse events.

Conclusions: Treatment of postmenopausal osteoporosis with strontium ranelate leads to early and sustained reductions in the risk of vertebral fractures.”

https://pubmed.ncbi.nlm.nih.gov/16910420/

“Clinical trials (phase III) have proved the efficiency of strontium ranelate in postmenopausal osteoporosis treatment. Strontium ranelate is a drug characterized by the new paradigm of action mechanism on bone, which has its place among the already well-proven drugs in postmenopausal osteoporosis treatment.”

https://pubmed.ncbi.nlm.nih.gov/18512789/

“Our findings indicate that treatment of postmenopausal osteoporosis with strontium ranelate results in a sustained reduction in the incidence of osteoporotic nonvertebral fractures, including hip fractures, and vertebral fractures over 5 years.”

https://pubmed.ncbi.nlm.nih.gov/19783590/

Adherence to treatment in the trials exceeded 80%, and the adverse event profile of SR was similar to that of placebo. Taken together, these long-term findings clearly demonstrate that SR is safe and effective in reducing both vertebral and non-vertebral (particularly hip) fracture risks for at least 5 years of pre-planned follow-up.

Strontium ranelate, a strontium(II) salt of ranelic acid. If I had to guess, the change from “safe and effective” to, “you can’t have it,” may have something to do with inability to patent natural ingredients? IDK. The terribly expensive drugs available in the USA are terrible imho.

https://pubmed.ncbi.nlm.nih.gov/29924137/ (helpful in OA)

https://strwebprdmedia.blob.core.windows.net/media/prvhadyx/ros-strontium-ranelate.pdf

https://www.sciencedirect.com/science/article/pii/S0928493116319488?ref=pdf_download&fr=RR-2&rr=939daa6b1bca2f03

https://pubmed.ncbi.nlm.nih.gov/12171530/

https://pubmed.ncbi.nlm.nih.gov/16787205/

“All these results suggest that strontium ranelate is a new, effective and safe treatment of vertebral and non-vertebral osteoporosis, with a unique mode of action.”

https://pubmed.ncbi.nlm.nih.gov/15578158/

“Strontium ranelate thus offers significant clinical benefits in terms of efficacy, tolerability, and ease of administration in the treatment of postmenopausal women with vertebral osteoporotic fractures.”

https://pubmed.ncbi.nlm.nih.gov/15728210/

“Strontium ranelate increased bone mineral density throughout the study, reaching at 3 yr (P < 0.001): +8.2% (femoral neck) and +9.8% (total hip). Incidence of adverse events (AEs) was similar in both groups.

Conclusion: This study shows that strontium ranelate significantly reduces the risk of all nonvertebral and in a high-risk subgroup, hip fractures over a 3-yr period, and is well tolerated. It confirms that strontium ranelate reduces vertebral fractures. Strontium ranelate offers a safe and effective means of reducing the risk of fracture associated with osteoporosis.

https://pubmed.ncbi.nlm.nih.gov/14749454/

“Strontium ranelate increased bone mineral density at month 36 by 14.4 percent at the lumbar spine and 8.3 percent at the femoral neck (P<0.001 for both comparisons). There were no significant differences between the groups in the incidence of serious adverse events.

Conclusions: Treatment of postmenopausal osteoporosis with strontium ranelate leads to early and sustained reductions in the risk of vertebral fractures.”

https://pubmed.ncbi.nlm.nih.gov/16910420/

“Clinical trials (phase III) have proved the efficiency of strontium ranelate in postmenopausal osteoporosis treatment. Strontium ranelate is a drug characterized by the new paradigm of action mechanism on bone, which has its place among the already well-proven drugs in postmenopausal osteoporosis treatment.”

https://pubmed.ncbi.nlm.nih.gov/18512789/

“Our findings indicate that treatment of postmenopausal osteoporosis with strontium ranelate results in a sustained reduction in the incidence of osteoporotic nonvertebral fractures, including hip fractures, and vertebral fractures over 5 years.”

https://pubmed.ncbi.nlm.nih.gov/19783590/

Adherence to treatment in the trials exceeded 80%, and the adverse event profile of SR was similar to that of placebo. Taken together, these long-term findings clearly demonstrate that SR is safe and effective in reducing both vertebral and non-vertebral (particularly hip) fracture risks for at least 5 years of pre-planned follow-up.

https://pubmed.ncbi.nlm.nih.gov/19783589/

“Finally, SR significantly attenuated height loss and decreased back pain. The safety profile of SR was almost similar to placebo in both trials. Thus, SR demonstrates broad spectrum safety and efficacy in reducing the risks of both vertebral and non-vertebral (including hip) fractures in a wide variety of patients, and should be considered as a first-line option to treat women at risk of osteoporotic fractures, whatever their age, the severity of the disease and their risk factors.”

Articles that do not advise:

A prescription form of strontium—strontium ranelate (the ranelate salt), known as Protelos/Osseor®— was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip.

Incr risk of pulmonary emboli and heart probs (in elderly, sedentary?)

https://americanbonehealth.org/medications-bone-health/why-strontium-is-not-advised-for-bone-health/

https://pubmed.ncbi.nlm.nih.gov/16910420/ (“no difference between SR and SCl”)

The effective compound is strontium ranelate. Available sources in USA are the ineffective citrate. Didn’t we see something like this with red yeast rice? Hmm…

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Fred's avatar

...nonvertebral and in a high-risk subgroup, hip fractures over a 3-yr period, and is well tolerated. It confirms that strontium ranelate reduces vertebral fractures. Strontium ranelate offers a safe and effective means of reducing the risk of fracture associated with osteoporosis.

https://pubmed.ncbi.nlm.nih.gov/14749454/

“Strontium ranelate increased bone mineral density at month 36 by 14.4 percent at the lumbar spine and 8.3 percent at the femoral neck (P<0.001 for both comparisons). There were no significant differences between the groups in the incidence of serious adverse events.

Conclusions: Treatment of postmenopausal osteoporosis with strontium ranelate leads to early and sustained reductions in the risk of vertebral fractures.”

https://pubmed.ncbi.nlm.nih.gov/16910420/

“Clinical trials (phase III) have proved the efficiency of strontium ranelate in postmenopausal osteoporosis treatment. Strontium ranelate is a drug characterized by the new paradigm of action mechanism on bone, which has its place among the already well-proven drugs in postmenopausal osteoporosis treatment.”

Expand full comment
Fred's avatar

https://pubmed.ncbi.nlm.nih.gov/18512789/

“Our findings indicate that treatment of postmenopausal osteoporosis with strontium ranelate results in a sustained reduction in the incidence of osteoporotic nonvertebral fractures, including hip fractures, and vertebral fractures over 5 years.”

https://pubmed.ncbi.nlm.nih.gov/19783590/

Adherence to treatment in the trials exceeded 80%, and the adverse event profile of SR was similar to that of placebo. Taken together, these long-term findings clearly demonstrate that SR is safe and effective in reducing both vertebral and non-vertebral (particularly hip) fracture risks for at least 5 years of pre-planned follow-up.

https://pubmed.ncbi.nlm.nih.gov/19783589/

“Finally, SR significantly attenuated height loss and decreased back pain. The safety profile of SR was almost similar to placebo in both trials. Thus, SR demonstrates broad spectrum safety and efficacy in reducing the risks of both vertebral and non-vertebral (including hip) fractures in a wide variety of patients, and should be considered as a first-line option to treat women at risk of osteoporotic fractures, whatever their age, the severity of the disease and their risk factors.”

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Fred's avatar

From the "not advised" column:

A prescription form of strontium—strontium ranelate (the ranelate salt), known as Protelos/Osseor®— was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip.

Incr risk of pulmonary emboli and heart probs (in elderly, sedentary?)

https://americanbonehealth.org/medications-bone-health/why-strontium-is-not-advised-for-bone-health/

https://pubmed.ncbi.nlm.nih.gov/16910420/ (“no difference between SR and SCl”)

The effective compound is strontium ranelate. Available sources in USA are the ineffective citrate. Didn’t we see something like this with red yeast rice? Hmm…

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Elle's avatar

Where can we find studies that show strontium citrate ineffective? I’ve read the ranelate study that went for 7 years with no difference with the placebos.

Do you have sources on trying the citrate? It’s being sold along with calcium mineral compound here in the US, quite expensive. They claim it’s guaranteed to work but the study for reference is the one using the ranelate.

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Fred's avatar

No I don’t; however, if it was effective it would have gone the way of ranelate, when the studies showed benefit.

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Frank Priebe's avatar

This was a great one. #JulySurprise.

Shannon Joy show with Dr. David Martin

https://rumble.com/v6szjm3--flourishing-amidst-emerging-chaos.-no-one-is-coming-to-save-us-embracing-t.html

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Lili's avatar

I'd like to know more about the use of topical progesterone. Anyone have a good source?

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Thomas A Braun RPh's avatar

Disappointed not more said about the key role of vitamin D. Works with Magnesium, Calcium and K2 for maintaining bone health. A 30 million Women's Health initiative programmed by Lilly and paid for the US taxpayers discredited estrogen and it's role for good health. They scammed the research by having the women selected for the study to be 10 years older on average to create more disease states to be present. George Bush helped to make it happen. Got Lilly's osteoclast killing chemo to be profitable. Stopped old bone from being destroyed.

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Dr Kay's avatar

My thoughts have been that the brittle bone phenomenon that has been happening to older people is due to fluoride added to pretty much every processed food/drink sold across America. If there's liquid, its probably in there.....canned, jarred, bottled; even in the majority of bottled waters that fill the water coolers at work. It's in there. Fluoride bioaccumulates in the bones....and makes them heavy, and brittle. So that makes sense to me. I do know a lot of older people who have ended up with broken bones which landed them in nursing homes.....I worked in the nursing home industry for over ten years, and this was common. So something is happening. It's been blamed on "osteoporosis".....but we all know the lies of the medical cult.

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Anon E. Mousse's avatar

It is dangerous to dwell in the land of half-truth and more dangerous still to persuade others to join in.

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Troy's avatar

Forgot one of the most if not THE most important factors in healthy bones and that’s protein. Our bones are made up of approximately 40% protein and the best kind to consume is animal protein. It’s why the elderly have such weak bones, because doctors tell them they need to eat less because it’s hard on their kidneys which is complete rubbish.

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Mike Stephenson's avatar

I had primary hyperparathyroidism (pHPT) for 10 years before it was picked up by an endocrinologist that I was sent to for another issue. I had high blood calcium for 10 years and it was missed by multiple physicians. The endo ordered all the right labs (Calcium, Vitamin D, parathyroid hormone aka PTH). I had had a kidney stone, a symptom of pHPT, in 2019 (very painful) but not diagnosed until Sept 2023. I was cured by surgery in April 2024. I had osteopenia (spine) and osteoporosis (hip, arm/wrist). One year post surgery, my spine is now normal, well out of osteopenia range. Still have work to do on the other two areas but they are also improved from a year ago.

I am not taking any drugs. I am taking testosterone for bone rebuilding and calcium, vitamin D, vitamin K2 MK4 (high dose, 45 mg/day). Also taking boron.

Most people when they hear parathyroid think you said thyroid! Para means nearby or adjacent to so the parathyroids are near the thyroid (usually but not always). Most people have 4 parathyroid glands, but some have more than four! It's very easily cured with a very experienced parathyroid surgeon.

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John Roberts's avatar

It might be easier if we had a list of what drugs are truly safe, if there is even a list at all. !!!

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Kathlean J Keesler's avatar

Wow thank you (age 67) Olympia WA

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RebelGhirl's avatar

Ty for this. Sent to my mom bc the doc was trying to tell my Dad he far osteoporosis. We were all skeptical. 🤨

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OldGuyAdventure's avatar

I was told when I was diagnosed with Klinefelter's Syndrome that osteoporosis was a big threat, as I did not produce enough testosterone and my bones would erode. Simultaneously, the doctor stated that they typically do not prescribe testosterone to individuals exhibiting Klinefelter's syndrome, as they view the condition as non-life-threatening. However, didn't she mention that a lack of testosterone could lead to bone erosion? This indicates that the body continues to crave calcium and will extract it from other sources due to a hormonal deficiency. Indeed, this scenario appears to be potentially fatal. In my experience over the past 35 years of taking testosterone, the medical system in Canada uses the hormone for control. On the one hand, they say it is not critical to have it and then cut me off for months on end, and on the other hand, they wonder why I seem to be getting shorter.

In the past, I was prescribed a statin and subsequently wondered why my sex drive and cognitive abilities declined. So as an offset, the doctor increases the injected testosterone, which in turn results in acne and lesions. But he never clued in that the statin is depleting my naturally produced testosterone because it is limiting the LDL that makes it.

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